Study Compares Human and Synthetic Vertebrae for Testing Interbody Devices

Spine

A recent study published in Spine compared subsidence measures of bone surrogates with human vertebrae to assess the varying size and placement of interbody devices. Researchers placed indentors on synthetic vertebrae endplates, foam blocks and human vertebrae and subjected them to uniaxial compression. The subsidence measures in the human vertebrae showed variation with indentor placement and failure forces were higher with peripheral placement.

The subsidence measurements with the foam blocks were shown to be insensitive to indentor size and placement. They showed a similar response to the human vertebrae for centrally placed indentors. In the synthetic vertebrae, subsidence measurements were sensitive to indentor size and placement while failure force and indentation stiffness was over-estimated.

Read the report on placement for interbody devices.

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