A research group, led by researchers at the Cleveland Clinic, found a one-time injection of fibronectin immediately after spinal cord injury can limit pain for up to eight months, according to a news release.
Fibronectin is a naturally occurring protein that supports the survival, growth and communication of neurons in the brain and spinal cord. Researchers found an injection of fibronectin into the spinal cord triggers specific signaling pathways and inhibits the development of chronic pain.
While researchers don't understand the exact mechanisms of the connection between fibronectin and pain relief, study results showed fibronectin maintained the integrity of the blood-spinal cord barrier and suppressed the inflammatory response. Researchers also found fibronectin reversed decreases in serotonin, which influences pain perception, due to spinal cord injury.
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While researchers don't understand the exact mechanisms of the connection between fibronectin and pain relief, study results showed fibronectin maintained the integrity of the blood-spinal cord barrier and suppressed the inflammatory response. Researchers also found fibronectin reversed decreases in serotonin, which influences pain perception, due to spinal cord injury.
Related Articles on Pain Management:
Dr. Andrew C. Charles Named First Luskin Chair in Migraine and Headache Studies at UCLA
Global Anesthesia Disposables Market to Reach $343.5M by 2017
DSM Collaborates with AdeTherapeutics to Develop Pain Management and Scar Reduction Product for Spine Surgeries