Misonix entered into a distribution agreement with Lithuania-based Apex Medicus to distribute its SonaStar Ultrasonic Aspirator and BoneScalpel Ultrasonic Bone Cutter.

The U.S. Department of Justice announced it would end its four year investigation related to off-label use of Medtronic's Infuse for spinal fusions.

AxioMed Spine Corp. has announced it has received the CE mark approval for its Freedom cervical disc, according to a news release.

Mazor Robotics, an Israel-based robotic spinal system company and developer of the Renaissance system, reported $2.4 million in revenue for the first quarter of 2012, an increase over the same period last year.

The Food and Drug Administration granted 14 spine device-related clearances in April, according to an FDA report.

TranS1, a Wilmington, N.C.-based spine device company, reported a 26 percent decrease in revenue for the first quarter of 2012.

Alphatec Spine reported first quarter revenue of $48.5 million, slightly less than the same period last year.

Here are 20 orthopedic and spine device company leadership moves so far this year.

The Food and Drug Administration granted 33 orthopedic- and spine-related device clearances in April.

Jupiter, Fla.-based company BioRestorative Therapies has announced improvements in the latest version of its stem cell disc delivery device, which is used for treating bulging and herniated discs.