Researchers analyzed PubMed for prospective, original, English-language studies published between 2004 and 2010 about thromboprophylaxis after TJA. There were 71 articles identified and 52 articles were industry-funded. There were 14 articles not funded by the industry and five articles that did not include information about the funding source.
The study found:
• 3.8 percent of the 52 industry-sponsored studies have unfavorable conclusions
• 21.4 percent of the 14 non-industry sponsored studies showed that prophylactic agents were not effective or safe, depending on the situation
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Industry-Sponsored Studies on Thromboprophylaxis After Joint Replacement May Hold Bias
Written by Laura Miller | February 21, 2012
A recent review of articles examining thromboprophylaxis after total joint arthroplasty found that most studies are sponsored by the industry and conclusions in those studies are favorable to the use of prophylactic agents, according to a report in the Journal of Bone and Joint Surgery.
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